Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
14. Genetic Control of Development
Developmental Patterning Genes
3:23 minutes
Problem 13c
Textbook Question
Textbook QuestionThe bicoid gene is a coordinate maternal–effect gene.
A female Drosophila heterozygous for a loss-of function bicoid allele is mated to a male that is heterozygous for the same allele. What are the phenotypes of their progeny?
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Bicoid Gene Function
The bicoid gene is crucial for establishing the anterior-posterior axis in Drosophila embryos. It encodes a transcription factor that regulates the expression of other genes necessary for head and thorax development. A loss-of-function mutation in this gene leads to the absence of anterior structures, resulting in embryos that lack head and thoracic segments.
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Maternal Effect Genes
Maternal effect genes are genes expressed in the mother that influence the phenotype of the offspring, regardless of the offspring's genotype. In the case of the bicoid gene, the maternal contribution of bicoid mRNA and protein is essential for proper embryonic development. If the mother is heterozygous for a loss-of-function allele, the progeny may inherit varying levels of functional bicoid protein, affecting their phenotypes.
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Genotype and Phenotype Relationship
The genotype refers to the genetic constitution of an organism, while the phenotype is the observable physical or biochemical characteristics. In this scenario, the progeny of a cross between two heterozygous parents (one with a loss-of-function allele) will exhibit a range of phenotypes based on the combination of alleles inherited. Understanding this relationship is key to predicting the phenotypic outcomes in the offspring.
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