Har Gobind Khorana and his colleagues performed numerous...

Question

Har Gobind Khorana and his colleagues performed numerous experiments translating synthetic mRNAs. In one experiment, an mRNA molecule with a repeating UG dinucleotide sequence was assembled and translated.

What is the sequence of the resulting polypeptide?

Accepted Answer

Hey, everyone. Let's take a look at this question together. How many types of polypeptides will be observed by a researcher who uses trinucleotide repeats to form a synthetic M R N A. Is it answer choice? A one answer, choice B two, answer choice C three or answer choice D four. Let's work this problem out together to try to figure out how many types of polypeptides will be observed. So we have our researcher who is using trinucleotide repeats in their synthetic M R N A. And what we mean by trinucleotide repeats is that we are repeating three nucleotides. So for example, let's say we are using the trinucleotide repeat of U U C where we can have either U U C U C U or C U U as our trinucleotide repeat. And so we have our first sequence which can have those trinucleotide repeats of U U C. So we have the repeat of U U C for however long that M R N A sequence is and we can also have that sequence involving the trinucleotide repeats of U C U which also repeats for however long that synthetic M R N A sequence is. And lastly, we can also have those repeats of C U U or however long, our synthetic M R N A sequence is, which means we have a total of 12 and three types of polypeptides. Since we can have three different codons using those trinucleotide repeats, which means that answer choice. C three is the correct answer because we have those trinucleotide repeats, which means that we have those repeats of three nucleotides. And in our example, we are using U U C which can have the repeating codon of U U C U C U or C U U, which means that we have 12 and three different types of polypeptides making answer choice. C the correct answer. I hope you found this video to be helpful. Thank you and goodbye.

Har Gobind Khorana and his colleagues performed numerous experiments translating synthetic mRNAs. In one experiment, an mRNA molecule with a repeating UG dinucleotide sequence was assembled and translated.

What is the sequence of the resulting polypeptide?

Key Concepts

mRNA Translation

Codons and Amino Acids

UG Dinucleotide Sequence

Watch next

Har Gobind Khorana and his colleagues performed numerous experiments translating synthetic mRNAs. In one experiment, an mRNA molecule with a repeating UG dinucleotide sequence was assembled and translated.What is the sequence of the resulting polypeptide?

Key Concepts

mRNA Translation

Codons and Amino Acids

UG Dinucleotide Sequence

Watch next

Har Gobind Khorana and his colleagues performed numerous experiments translating synthetic mRNAs. In one experiment, an mRNA molecule with a repeating UG dinucleotide sequence was assembled and translated.

What is the sequence of the resulting polypeptide?