Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
4. Genetic Mapping and Linkage
Mapping Genes
5:59 minutes
Problem 18c
Textbook Question
Textbook QuestionThe Rh blood group in humans is determined by a gene on chromosome 1. A dominant allele produces Rh+ blood type, and a recessive allele generates Rh-. Elliptocytosis is an autosomal dominant disorder that produces abnormally shaped red blood cells that have a short life span resulting in hereditary anemia. A large family with elliptocytosis is tested for genetic linkage of Rh blood group and the disease. The lod score data below are obtained for the family.
From these data, can you conclude that Rh and elliptocytosis loci are genetically linked in this family? Why or why not?
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