The following pedigree shows a family in which several i...

Question

The following pedigree shows a family in which several individuals exhibit symptoms of the mitochondrial disease MERRF. Two siblings (II-2 and II-5) approach you to inquire about whether their children will also be afflicted with MERRF. What do you tell them?

Pedigree chart showing family members with MERRF symptoms for genetics course.

Accepted Answer

Although everyone here, we have a question that says the following pedigree shows the inheritance of an unknown disease. Z and a family examine the pedigree carefully and choose which of the following best explains the inheritance of the disease Z and the individuals of the third generation. So we have our first generation and we have one which is a male that is unaffected. We have two which is a female that is affected. We have three which is a male that is unaffected and we have four which is a female that is unaffected. And in the second generation, we have one which is an unaffected male to which is an affected female. Three, an affected female, four, an affected male, five and affected female. Six, an affected male, seven and unaffected female. And then our third generation, we have won an unaffected female to an unaffected male. Three, an unaffected male, four and unaffected female, five and unaffected female And six and unaffected female. And her answer choices are unaffected and 3456 affected B 3123 affected and 3456, unaffected C 3123 affected and 3456 affected D unaffected and 3456 unaffected. So the pedigree shows that the inheritance of Z is maternal and not paternal. So that is why all the individuals are affected in the second generation suggests that the mother I two is home A Plas Mick. So all of the Children of generation 22 will be affected and that of 26 will be unaffected. So our answer here is b thank you for watching. Bye.

The following pedigree shows a family in which several individuals exhibit symptoms of the mitochondrial disease MERRF. Two siblings (II-2 and II-5) approach you to inquire about whether their children will also be afflicted with MERRF. What do you tell them?

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