Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
2. Mendel's Laws of Inheritance
Dihybrid Cross
4:41 minutes
Problem 15
Textbook Question
Textbook QuestionIn a study of black guinea pigs and white guinea pigs, 100 black animals were crossed with 100 white animals, and each cross was carried to an F₂ generation. In 94 of the crosses, all the F₁ offspring were black and an F₂ ratio of 3 black:1 white was obtained. In the other 6 cases, half of the F₁ animals were black and the other half were white. Why? Predict the results of crossing the black and white F₁ guinea pigs from the 6 exceptional cases.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Mendelian Genetics
Mendelian genetics is the study of how traits are inherited through generations, based on the principles established by Gregor Mendel. It includes concepts such as dominant and recessive alleles, where dominant traits mask the expression of recessive ones. In this case, black fur is likely a dominant trait over white fur, explaining the 3:1 ratio in the F₂ generation.
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Descriptive Genetics
Genotype and Phenotype
The genotype refers to the genetic makeup of an organism, while the phenotype is the observable physical or biochemical characteristics. In the crosses described, the F₁ generation's phenotype (black or white fur) is influenced by their genotype, which can be homozygous or heterozygous. The variation in F₁ offspring in the exceptional cases suggests different genotypes among the parents.
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Gamete Genotypes
Incomplete Dominance
Incomplete dominance occurs when the phenotype of heterozygous individuals is intermediate between those of the homozygous parents. In the six exceptional cases, the presence of both black and white offspring in the F₁ generation indicates that the black and white alleles may exhibit incomplete dominance, leading to a mix of phenotypes rather than a clear dominance.
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Variations on Dominance
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