Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
21. Population Genetics
Allelic Frequency Changes
2:33 minutes
Problem 35
Textbook Question
Textbook QuestionThe following is a partial pedigree of the British royal family. The family contains several inbred individuals and a number of inbreeding pathways. Carefully evaluate the pedigree, and identify the pathways and common ancestors that produce inbred individuals A (Alice in generation IV), B (George VI in generation VI), and C (Charles in generation VIII).
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Pedigree Analysis
Pedigree analysis is a method used to study the inheritance patterns of traits in families. It involves creating a diagram that represents family relationships and the transmission of genetic traits across generations. By analyzing the pedigree, one can identify carriers of specific traits, determine the likelihood of inheritance, and trace the lineage of individuals, which is crucial for understanding inbreeding and its effects.
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Inbreeding
Inbreeding refers to the mating of individuals who are closely related genetically, which can lead to an increased chance of offspring inheriting genetic disorders. In a pedigree, inbreeding can be identified by the presence of multiple affected individuals in a lineage, often resulting from common ancestors. Understanding inbreeding is essential for evaluating the health and genetic diversity of a population, particularly in royal families where such practices have historically occurred.
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Common Ancestors
Common ancestors are individuals from whom two or more descendants inherit genetic material. In the context of a pedigree, identifying common ancestors is vital for tracing inbreeding pathways, as these ancestors contribute to the genetic makeup of inbred individuals. Recognizing these relationships helps in understanding how traits are passed down and the potential risks associated with inbreeding, such as reduced genetic diversity and increased likelihood of recessive genetic disorders.
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