Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
7. DNA and Chromosome Structure
DNA as the Genetic Material
2:44 minutes
Problem 4b
Textbook Question
Textbook QuestionContrast the contributions made to an understanding of transformation by Griffith and by Avery and his colleagues.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Griffith's Experiment
Frederick Griffith's 1928 experiment with Streptococcus pneumoniae demonstrated the phenomenon of transformation, where non-virulent bacteria could acquire virulence from heat-killed virulent strains. This pivotal study suggested that some 'transforming principle' was responsible for this genetic change, laying the groundwork for future genetic research.
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Mendel's Experiments
Avery's Discovery
In 1944, Oswald Avery and his colleagues built upon Griffith's findings by identifying DNA as the 'transforming principle.' They conducted experiments that showed only DNA from virulent strains could transform non-virulent strains, providing strong evidence that DNA is the molecule responsible for heredity and genetic information.
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Discovery
Transformation in Genetics
Transformation is a process in genetics where a cell takes up foreign DNA from its environment, leading to a change in its genotype and phenotype. This mechanism is crucial for understanding genetic variation and has significant implications in molecular biology, biotechnology, and genetic engineering.
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Transformation
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