Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
15. Genomes and Genomics
Genomics and Human Medicine
2:44 minutes
Problem 14h
Textbook Question
Textbook QuestionHow has the use of model organisms advanced our knowledge of the genes that control human diseases?
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Model Organisms
Model organisms are non-human species that are extensively studied to understand biological processes. They are chosen for their genetic, biological, or behavioral similarities to humans, allowing researchers to investigate gene functions and disease mechanisms. Common examples include mice, fruit flies, and zebrafish, which serve as valuable tools in genetics and biomedical research.
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Genetic Homology
Genetic homology refers to the similarity in DNA sequences between different species due to shared ancestry. This concept is crucial in model organism research, as it allows scientists to extrapolate findings from model organisms to humans. By studying genes in these organisms, researchers can identify conserved pathways and potential targets for treating human diseases.
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Transgenic Techniques
Transgenic techniques involve the introduction of foreign DNA into an organism's genome, enabling the study of gene function and regulation. These methods allow researchers to create models that mimic human diseases, facilitating the investigation of genetic contributions to conditions such as cancer and neurodegenerative disorders. This approach has significantly advanced our understanding of disease mechanisms and potential therapeutic strategies.
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