Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
6. Chromosomal Variation
Chromosomal Mutations: Aberrant Euploidy
2:36 minutes
Problem 9b
Textbook Question
Textbook QuestionMating between a male donkey (2n=62) and a female horse (2n=64) produces sterile mules. Recently, however, a very rare event occurred—a female mule gave birth to an offspring by mating with a horse.
How many chromosomes does the mule–horse offspring carry?
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Chromosome Number in Species
Different species have distinct chromosome numbers, which are crucial for understanding hybridization. In this case, the male donkey has 62 chromosomes, while the female horse has 64. The resulting mule, a hybrid, typically has an intermediate chromosome count of 63, but is usually sterile due to the mismatch in chromosome numbers.
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Hybrid Sterility
Hybrid sterility occurs when the offspring of two different species are unable to reproduce. Mules, resulting from the mating of a donkey and a horse, are generally sterile because their uneven chromosome count prevents proper gamete formation. However, rare exceptions, like the female mule in this scenario, can occur, leading to potential reproduction.
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Chromosome Contribution in Offspring
When two organisms mate, the offspring inherit a combination of chromosomes from both parents. In this case, if the female mule (63 chromosomes) mates with a horse (64 chromosomes), the offspring could inherit a mix of these chromosomes. The possible chromosome counts for the mule-horse offspring could be 63 or 64, depending on the gametes contributed by the mule.
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