Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
10. Transcription
Transcription in Eukaryotes
2:05 minutes
Problem 4a
Textbook Question
Textbook QuestionThe diagram below shows a DNA duplex. The template strand is identified, as is the location of the nucleotide. If this region is a eukaryotic gene transcribed by RNA polymerase III, where are the promoter consensus sequences located? <>
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Eukaryotic Gene Structure
Eukaryotic genes typically consist of coding regions called exons and non-coding regions known as introns. The transcription of these genes is initiated at specific sites called promoters, which are located upstream of the coding sequence. Understanding the structure of eukaryotic genes is essential for identifying where transcription begins and how RNA polymerase interacts with the DNA.
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RNA Polymerase III
RNA polymerase III is one of the three main types of RNA polymerases in eukaryotic cells, primarily responsible for transcribing small RNA molecules, including tRNA and 5S rRNA. It recognizes specific promoter sequences that are distinct from those used by RNA polymerase II, which transcribes mRNA. Knowing the role of RNA polymerase III helps in understanding the transcription process of certain genes.
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Promoter Consensus Sequences
Promoter consensus sequences are short, conserved sequences of nucleotides that are recognized by transcription factors and RNA polymerase to initiate transcription. In eukaryotic genes transcribed by RNA polymerase III, these sequences are typically located upstream of the transcription start site. Identifying these sequences is crucial for understanding how genes are regulated and expressed.
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