Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
2. Mendel's Laws of Inheritance
Pedigrees
3:28 minutes
Problem 47e
Textbook Question
Textbook QuestionThe accompanying pedigree shows a family in which one child (II-1) has an autosomal recessive condition. On the basis of this fact alone, provide the following information.
Using A for the dominant allele and a for the recessive allele, give the genotypes for I-1, I-2, and II-1. <>
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Autosomal Recessive Inheritance
Autosomal recessive inheritance occurs when a trait is expressed only when an individual has two copies of the recessive allele (aa). In this case, if a child has an autosomal recessive condition, both parents must either be carriers (Aa) or affected (aa) themselves. This means that the condition can skip generations, as carriers do not show symptoms.
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Genotype Notation
Genotype notation uses letters to represent alleles, where uppercase letters denote dominant alleles and lowercase letters denote recessive alleles. For example, 'A' represents the dominant allele, while 'a' represents the recessive allele. Understanding this notation is crucial for determining the genotypes of individuals based on their phenotypes and family history.
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Pedigree Analysis
Pedigree analysis is a method used to trace the inheritance of traits through generations in a family. It visually represents family relationships and the presence of specific traits, allowing for the identification of carriers and affected individuals. By analyzing the pedigree, one can infer the genotypes of family members based on the inheritance patterns observed.
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