Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
4. Genetic Mapping and Linkage
Crossing Over and Recombinants
3:50 minutes
Problem 13b
Textbook Question
Textbook QuestionTwo different female Drosophila were isolated, each heterozygous for the autosomally linked genes b (black body), d (dachs tarsus), and c (curved wings). These genes are in the order d–b–c, with b being closer to d than to c. Shown here is the genotypic arrangement for each female along with the various gametes formed by both: Identify which categories are noncrossovers (NCOs), single crossovers (SCOs), and double crossovers (DCOs) in each case. Then, indicate the relative frequency in which each will be produced.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Genetic Linkage
Genetic linkage refers to the tendency of genes located close to each other on a chromosome to be inherited together during meiosis. This phenomenon affects the assortment of alleles and can lead to nonrandom combinations of traits in offspring. Understanding linkage is crucial for predicting gamete formation and the inheritance patterns of linked genes.
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Chi Square and Linkage
Types of Crossovers
Crossovers occur during meiosis when homologous chromosomes exchange genetic material. Noncrossovers (NCOs) result in gametes that are identical to the parental types, while single crossovers (SCOs) produce gametes with a mix of parental alleles. Double crossovers (DCOs) involve two crossover events and can result in gametes that are less frequent due to the complexity of the events involved.
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Types of Maternal Inheritance
Recombination Frequency
Recombination frequency is a measure of how often crossovers occur between two genes during meiosis, influencing the genetic map distance between them. It is calculated based on the proportion of recombinant gametes produced compared to the total number of gametes. This frequency helps in determining the relative positions of genes on a chromosome and understanding the likelihood of different crossover types.
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