Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
7. DNA and Chromosome Structure
DNA Structure
2:08 minutes
Problem 5d
Textbook Question
Textbook QuestionOne strand of a fragment of duplex DNA has the sequence 5'-ATCGACCTGATC-3'.
Identify the bond that joins one strand of a DNA duplex to the other strand.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Hydrogen Bonds
Hydrogen bonds are weak interactions that occur between the nitrogenous bases of the two DNA strands. In a DNA duplex, adenine pairs with thymine through two hydrogen bonds, while cytosine pairs with guanine through three hydrogen bonds. These bonds are crucial for the stability of the DNA double helix, allowing the strands to separate during processes like replication and transcription.
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Base Pairing Rules
Base pairing rules dictate how nitrogenous bases in DNA pair with each other. Specifically, adenine (A) pairs with thymine (T), and cytosine (C) pairs with guanine (G). This complementary pairing is essential for the accurate replication of DNA and the transmission of genetic information, ensuring that the genetic code is preserved across generations.
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Base Distortions
DNA Structure
DNA is structured as a double helix, consisting of two antiparallel strands that are held together by base pairs. Each strand is composed of a sugar-phosphate backbone and nitrogenous bases that extend inward. The antiparallel nature of the strands (one running 5' to 3' and the other 3' to 5') is critical for the mechanisms of DNA replication and transcription, influencing how enzymes interact with the DNA.
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