In this chapter, we focused on the translation of mRNA into proteins as well as on protein structure and function. Along the way, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations in the chapter, what answers would you propose to the following fundamental questions:
What experimentally derived information led to Holley's proposal of the two-dimensional cloverleaf model of tRNA?
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
11. Translation
Transfer RNA
0:59 minutes
Problem 11cSanders - 3rd Edition
Textbook Question
Textbook QuestionConsider translation of the following mRNA sequence:
5′-...AUGCAGAUCCAUGCCUAUUGA...-3′
Diagram translation at the moment the fourth amino acid is added to the polypeptide chain. Show the ribosome; label its A, P, and E sites; show its direction of movement; and indicate the position and anticodon triplet sequence of tRNAs that are currently interacting with mRNA codons.
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