Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
17. Mutation, Repair, and Recombination
Induced Mutations
1:08 minutes
Problem 17b
Textbook Question
Textbook QuestionIn 2013 the actress Angelina Jolie elected to have prophylactic double-mastectomy surgery to prevent breast cancer based on a positive test for mutation of the BRCA1 gene. What are some potential positive and negative consequences of this high-profile example of acting on the results of a genetic test?
Verified Solution
This video solution was recommended by our tutors as helpful for the problem above
Video duration:
1mPlay a video:
Was this helpful?
Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
BRCA1 Gene and Its Role in Cancer
The BRCA1 gene is a crucial gene that produces a protein responsible for repairing damaged DNA. Mutations in this gene can significantly increase the risk of breast and ovarian cancers. Understanding the implications of BRCA1 mutations is essential for assessing cancer risk and making informed medical decisions, such as prophylactic surgeries.
Recommended video:
Guided course
09:51
Cancer Characteristics
Prophylactic Surgery
Prophylactic surgery, such as a double mastectomy, is a preventive measure taken to reduce the risk of developing cancer in individuals with a high genetic predisposition. This surgical option can significantly lower the chances of cancer but also involves physical, emotional, and psychological consequences that must be carefully considered by patients.
Public Perception and Genetic Testing
High-profile cases like Angelina Jolie's can influence public perception of genetic testing and preventive measures. While they can raise awareness and encourage individuals to seek genetic testing, they may also lead to misconceptions about the risks and benefits, potentially resulting in pressure to undergo similar procedures without fully understanding the implications.
Recommended video:
Guided course
11:35
History of Genetics
Watch next
Master Induced Mutations with a bite sized video explanation from Kylia Goodner
Start learningRelated Videos
Related Practice