Har Gobind Khorana and his colleagues performed numerous...

Question

Har Gobind Khorana and his colleagues performed numerous experiments translating synthetic mRNAs. In one experiment, an mRNA molecule with a repeating UG dinucleotide sequence was assembled and translated.

Write the sequence of this mRNA and give its polarity.

Accepted Answer

Hey, everyone. Let's take a look at this question together. If a researcher uses dinucleotide repeats to form a synthetic M R N A, how many types of amino acids will the polypeptide have? Is it answer choice? A one answer, choice B two, answer choice C three or answer choice D four. Let's work this problem out together to try to figure out how many types of amino acids will be present in the polypeptide if the researcher uses dinucleotide repeats. So we know that our researcher is using dinucleotide repeats to form that synthetic M R N A which dinucleotide repeats refers to using two nucleotides repeated in the sequence. And for our example, let's go ahead and say that the two nucleotides are U and C or uracil and cytosine. So our example, synthetic M R N A will have that three end and then those dinucleotide repeats of our U and C. So they just keep repeating until the end of the strand. And we are able to see that we have a code on for U C U as well as C U C, which means that we have you different coons, which means that we have two amino acid types. Since the reading frame will produce those alternating codons of U C U and C U C in that synthetic M R N A strand in this example, and since we want to know how many types of amino acids will the polypeptide have, we know that we will have two amino acids. So answer choice B two is the correct answer. Since our researcher is using dinucleotide repeats to form that synthetic M R N A in which dinucleotide repeats is when you use two nucleotides repeated in the sequence. And in our example, we're going to use U and C as those two nucleotides that keep repeating until the end of the strand. So we have a sample synthetic M R N A in which that U and C keep repeating. And we can see that we have the alternating of that U C U and C U C codon, which means that we will have two amino acids. So answer choice B is the correct answer. I hope you found this video to be helpful. Thank you and goodbye.

Har Gobind Khorana and his colleagues performed numerous experiments translating synthetic mRNAs. In one experiment, an mRNA molecule with a repeating UG dinucleotide sequence was assembled and translated.

Write the sequence of this mRNA and give its polarity.

Key Concepts

mRNA Structure

Polarity of Nucleic Acids

Codons and Translation

Watch next

Har Gobind Khorana and his colleagues performed numerous experiments translating synthetic mRNAs. In one experiment, an mRNA molecule with a repeating UG dinucleotide sequence was assembled and translated.Write the sequence of this mRNA and give its polarity.

Key Concepts

mRNA Structure

Polarity of Nucleic Acids

Codons and Translation

Watch next

Har Gobind Khorana and his colleagues performed numerous experiments translating synthetic mRNAs. In one experiment, an mRNA molecule with a repeating UG dinucleotide sequence was assembled and translated.

Write the sequence of this mRNA and give its polarity.