What observations reveal that a 'telomere problem' exists during ...

Question

What observations reveal that a 'telomere problem' exists during eukaryotic DNA replication, and how did we learn of the solution to this problem?

Accepted Answer

Hello everyone and welcome to today's video. So the repeating TT G G G G or TT A G G G invertebrate sequences are synthesized under the direction of the enzyme blank resulting in the extension of the three prime overhang. So as answer choice A we have primate B is ligase C is DNA polymerase one and D is telomerase. Well, in order to solve this problem, let's first determine what is occurring in this question. So we have the three prime overhang and this is located at the end of the chromosome. So there is an enzyme that is going to be synthesizing these the this end of the chromosome and this is done. So the genetic material at the end of the chromosome is protected from degradation. So this and this area of the chromosome where we have these sequences is called the telomeres and protecting the chromosome from degradation or the generic material at that end from degradation is going to be the role of these stils. So extending these stirs and keep it and keeping them at the right length is going to be the role of the enzyme telomerase. And I hope this makes sense how telomeres are going to be worked by the enzyme telomerase are very similar terms. And this is going to allow us to link them together. So this is what we're going to be adding to this blank here. So the repeating sequences at the end or at these telomeres are going to be synthesized under the direction of the enzyme telomerase resulting in the extension of the three prime overhang at the end of the chromosome. So the correct answer for this question is going to be d to lure, I really hope this video helped you and I hope to see you on the next one.

What observations reveal that a 'telomere problem' exists during eukaryotic DNA replication, and how did we learn of the solution to this problem?

Key Concepts

Telomeres

DNA Replication

Telomerase

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