Answer the following questions concerning the accuracy o...

Question

Answer the following questions concerning the accuracy of DNA polymerase during replication.

Identify two mechanisms that can correct the kind of abnormality resulting from the circumstances identified in part (c).

Accepted Answer

Hi, everyone. Welcome back. Here's our next question in nucleotide excision repair, which of the following enzymes binds to the distorted DNA structure and uses its A T P A activity to unwind the DNA forming a bubble around the damaged region and thereby allowing the DNA cutting enzymes to excise it. A DNA polymerase B DNA ligase C DNA helicase or D DNA Glyco ase. Well, our key term to focus in on here when trying to remember which of these enzymes fulfills these activities is the phrase unwind the DNA. And when we think of unwinding DNA double helices, we should have our minds drawn to choice C DNA helicase again, that name is an easy one to remember. I think of DNA double helix and the helicase unwinds that helix. The other answer choices are enzymes that are involved in the repair process. But in different parts of it, choice. A DNA polymerase comes in after you have that bubble, we think of how polymerase add base to a chain and DNA polymerase ads base to replace the missing ones after the wrong base has been excised. So that's part of the process but not the enzyme that we're looking for. And then Joyce B, DNA ligase rejoins the DNA backbone at the very end of this process. So the wrong base has been excised. Correct ones have been put in and ligase just rejoins the whole strand into a continuous DNA strand, but not the enzyme we're looking for. So not our correct answer. And then the final choice D D DNA Glyco is an enzyme that recognizes and exercises damaged faces. But again, we're looking for the enzyme that unwinds the helix around an element of D N distorted DNA structure, allowing the enzymes that are going to excise that area and repair it to have access to the strand. And that is choice C DNA heli case. See you in the next video.

Answer the following questions concerning the accuracy of DNA polymerase during replication.

Identify two mechanisms that can correct the kind of abnormality resulting from the circumstances identified in part (c).

Key Concepts

DNA Polymerase Function

Proofreading Activity

Mismatch Repair System

Watch next

Answer the following questions concerning the accuracy of DNA polymerase during replication.Identify two mechanisms that can correct the kind of abnormality resulting from the circumstances identified in part (c).

Key Concepts

DNA Polymerase Function

Proofreading Activity

Mismatch Repair System

Watch next

Answer the following questions concerning the accuracy of DNA polymerase during replication.

Identify two mechanisms that can correct the kind of abnormality resulting from the circumstances identified in part (c).