Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
10. Transcription
Transcription in Prokaryotes
3:13 minutes
Problem 20e
Textbook Question
Textbook QuestionWrite a paragraph describing the abbreviated chemical reactions that summarize RNA polymerase-directed transcription.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Transcription Process
Transcription is the process by which RNA polymerase synthesizes RNA from a DNA template. It involves three main stages: initiation, elongation, and termination. During initiation, RNA polymerase binds to the promoter region of the gene, unwinding the DNA. In elongation, RNA nucleotides are added to the growing RNA strand complementary to the DNA template, and termination occurs when RNA polymerase reaches a termination signal, releasing the newly formed RNA molecule.
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mRNA Processing
RNA Polymerase
RNA polymerase is the enzyme responsible for catalyzing the transcription of DNA into RNA. It unwinds the DNA double helix and synthesizes a single-stranded RNA molecule by adding ribonucleotides in a sequence complementary to the DNA template. There are different types of RNA polymerases in eukaryotes, with RNA polymerase II specifically synthesizing messenger RNA (mRNA), which carries genetic information from DNA to ribosomes for protein synthesis.
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Promoter and Terminator Sequences
Promoter and terminator sequences are essential DNA regions that regulate transcription. The promoter is a specific sequence where RNA polymerase binds to initiate transcription, often containing specific motifs that enhance binding efficiency. The terminator sequence signals the end of transcription, causing RNA polymerase to detach from the DNA and release the newly synthesized RNA. These sequences ensure that genes are expressed at the right time and in the correct amounts.
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Sequencing Difficulties
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