Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
18. Molecular Genetic Tools
Methods for Analyzing DNA
2:21 minutes
Problem 17e
Textbook Question
Textbook QuestionVariable number tandem repeats (VNTRs) are repeating DNA sequences of about 15–100 bp in length, found both within and between genes. Why are they commonly used in forensics?
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Variable Number Tandem Repeats (VNTRs)
VNTRs are short, repeating sequences of DNA that vary in number among individuals. These sequences can be found in non-coding regions of the genome and are highly polymorphic, meaning they differ significantly between people. This variability makes VNTRs useful for genetic profiling, as they can serve as unique identifiers for individuals.
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Forensic DNA Analysis
Forensic DNA analysis involves the examination of biological samples to identify individuals based on their genetic material. VNTRs are particularly valuable in this field because their high variability allows for the differentiation of DNA profiles, making it easier to match suspects to crime scenes or exclude innocent individuals.
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Genetic Polymorphism
Genetic polymorphism refers to the occurrence of two or more genetically different alleles at a locus within a population. VNTRs exemplify this concept, as the number of repeats can vary widely among individuals, leading to distinct genetic markers. This diversity is crucial in forensic science, as it enhances the accuracy and reliability of DNA matching.
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