Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
5. Genetics of Bacteria and Viruses
Bacterial Transformation
3:01 minutes
Problem 21b
Textbook Question
Textbook QuestionPenicillin was first used in the 1940s to treat gonorrhea infections produced by the bacterium Neisseria gonorrhoeae. In 1984, according to the CDC, fewer than 1% of gonorrhea infections were caused by penicillin-resistant N. gonorrhoeae. By 1990, more than 10% of cases were penicillin-resistant, and a few years later the level of resistance was at greater than 95%. Almost every year the CDC issues new treatment guidelines for gonorrhea that identify the recommended antibiotic drugs and dosages.
What are the short-term implications of these frequent changes for physicians and clinics that treat sexually transmitted diseases like gonorrhea and for individuals infected with gonorrhea?
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Antibiotic Resistance
Antibiotic resistance occurs when bacteria evolve to resist the effects of medications that once effectively treated infections. In the case of Neisseria gonorrhoeae, the rapid increase in penicillin resistance highlights how bacteria can adapt quickly to selective pressures, such as the widespread use of antibiotics. This phenomenon complicates treatment options and necessitates ongoing research and adaptation in medical guidelines.
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Treatment Guidelines
Treatment guidelines are systematically developed statements that assist healthcare providers in making decisions about appropriate healthcare for specific clinical circumstances. The CDC's annual updates for gonorrhea treatment reflect the need to adapt to changing patterns of antibiotic resistance, ensuring that physicians have the most effective and current information to treat infections. These guidelines are crucial for maintaining effective patient care and public health.
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Public Health Implications
Frequent changes in treatment guidelines due to rising antibiotic resistance have significant public health implications. For physicians and clinics, this means they must stay informed and adjust their treatment protocols regularly, which can strain resources and training. For individuals infected with gonorrhea, these changes may lead to delays in effective treatment, increased risk of complications, and a greater likelihood of transmission, underscoring the importance of timely and effective medical intervention.
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