Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
3. Extensions to Mendelian Inheritance
Chi Square Analysis
4: minutes
Problem 30c
Textbook Question
Textbook QuestionDr. Ara B. Dopsis and Dr. C. Ellie Gans are performing genetic crosses on daisy plants. They self-fertilize a blue-flowered daisy and grow 100 progeny plants that consist of 55 blue-flowered plants, 22 purple-flowered plants, and 23 white-flowered plants. Dr. Dopsis believes this is the result of segregation of two alleles at one locus and that the progeny ratio is 1:2:1. Dr. Gans thinks the progeny phenotypes are the result of two epistatic genes and that the ratio is 9:3:4.
The two scientists ask you to resolve their conflict by performing chi-square analysis on the data for both proposed genetic mechanisms. For each proposed mechanism, fill in the values requested on the form the researchers have provided for your analysis.
Use the form below to calculate chi square for the 9:3:4 hypothesis of Dr. Gans. <>
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Alleles and Loci
Alleles are different versions of a gene that can exist at a specific locus, or position, on a chromosome. In the context of the daisy plants, the blue, purple, and white flower colors are determined by different alleles at a single locus. Understanding how these alleles segregate during reproduction is crucial for predicting the phenotypic ratios of the offspring.
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Chi-Square Analysis
Chi-square analysis is a statistical method used to determine if there is a significant difference between observed and expected frequencies in categorical data. In this case, it will help assess whether the observed flower color ratios in the progeny align with the expected ratios proposed by Dr. Dopsis (1:2:1) and Dr. Gans (9:3:4). This analysis is essential for validating or refuting the genetic hypotheses presented.
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Epistasis
Epistasis refers to the interaction between genes at different loci, where the expression of one gene can mask or modify the expression of another. Dr. Gans suggests that the flower color in daisies results from two epistatic genes, leading to a 9:3:4 ratio. Understanding epistasis is vital for interpreting complex inheritance patterns and the resulting phenotypic ratios in the progeny.
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