Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
4. Genetic Mapping and Linkage
Mapping Genes
3:39 minutes
Problem 8b
Textbook Question
Textbook QuestionGene G recombines with gene T at a frequency of 7%, and gene G recombines with gene R at a frequency of 4%.
Assuming that organisms with any desired genotype are available, propose a genetic cross whose result could be used to determine which of the proposed genetic maps is correct.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Recombination Frequency
Recombination frequency is a measure of the likelihood that two genes will be separated during meiosis due to crossing over. It is expressed as a percentage, indicating the proportion of offspring that exhibit recombinant phenotypes. In this case, gene G's recombination frequencies with genes T and R are 7% and 4%, respectively, which suggests their relative positions on a genetic map.
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Genetic Mapping
Genetic mapping is the process of determining the location of genes on a chromosome and the distances between them based on recombination frequencies. By analyzing the outcomes of genetic crosses, researchers can create maps that illustrate the arrangement of genes. The proposed genetic cross should be designed to reveal the arrangement of genes G, T, and R based on their recombination frequencies.
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Mapping Overview
Test Cross
A test cross involves breeding an individual with a homozygous recessive organism to determine the genotype of the first individual. This method helps reveal the genetic makeup of the organism in question by analyzing the phenotypes of the offspring. In the context of the question, a test cross involving gene G with known genotypes of genes T and R can help clarify their genetic relationships and validate the proposed genetic maps.
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