Genetic linkage mapping for a large number of families i...

Question

Genetic linkage mapping for a large number of families identifies 4% recombination between the genes for Rh blood type and elliptocytosis (see Problem 18). At the Rh locus, alleles R and r control Rh+ and Rh- blood types. Allele E producing elliptocytosis is dominant to the wild-type recessive allele e. Tom and Terri each have elliptocytosis, and each is . Tom's mother has elliptocytosis and is Rh- while his father is healthy and has Rh+. Terri's father is Rh+ and has elliptocytosis; Terri's mother is Rh- and is healthy.

What is the probability that a child of Tom and Terri who is Rh+ will have elliptocytosis?

Accepted Answer

Hey, everyone. Let's take a look at this question. Together, there are 600 total combinations in the offspring of a die hybrid cross. What is the number of recombinant type offspring? If this cross has a 40% recombination frequency, is it answer choice? A 240 answer choice B 360 answer choice C 600 or answer choice D 800. Let's work this problem out together to try to figure out which of the following answer choices is the number of recombinant type offspring in this cross. So the first step in this question is to recall the recombination frequency formula which we know we have the recombination frequency and we're gonna go ahead and abbreviate the recombination frequency as R F is equal to the number of recombinant divided by the total offspring. And we multiply this by 100% to get our frequency. And so for this question, our total number of offspring is and our recombination frequency which is RF is 40%. And we want to know the number of recombinant. So our recombinant Will be represented as the variable X. And so we have our RF which equals Equals the number of recombinant, which is represented as X divided by the total offspring, which is 600 multiplied by 100%. And so we can cancel out the 100% by changing this, two, So we have 0.4 equals x divided by 600. And we have to cancel out that 600 in the denominator. So we multiply both sides of the equation by 600 to cancel it out on one side. And we multiply this side by 600. So we have 600 multiplied by 0.4 equals X. And we know that 600 multiplied by 0. is equal to 240. So X equals 240 which is our number of recombinant, which means that answer choice. A 240 is the correct answer because we know That the recombination frequency or RF is represented as the number of recombinant divided by the total number of offspring multiplied by 100%. And in this case, we have our total offspring of 600, our recombination frequency of 40%. And we need to find out the number of recombinant. So we set up our equation as 0.4 which is 40% which equals X divided by 600. And we cancel out the 600 on the right side of our equation and multiply 0.4 by 600 we end up with X equaling 240 which is the number of recombinant. So answer choice A is the correct answer. I hope you found this video to be helpful. Thank you and goodbye.

My Courses

Chemistry

Biology

Math

Physics

Business

Social Sciences

Programming

Product & Marketing