Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
4. Genetic Mapping and Linkage
Mapping Genes
Problem 8a
Textbook Question
Textbook QuestionGene G recombines with gene T at a frequency of 7%, and gene G recombines with gene R at a frequency of 4%.
Draw two possible genetic maps for these three genes, and identify the recombination frequencies predicted for each map.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Recombination Frequency
Recombination frequency is a measure of the likelihood that two genes will be separated during meiosis due to crossing over. It is expressed as a percentage, indicating the proportion of offspring that exhibit a recombinant phenotype. For example, a recombination frequency of 7% between genes G and T suggests that 7% of the gametes will have a combination of alleles different from the parental types.
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Genetic Mapping
Genetic mapping involves determining the relative positions of genes on a chromosome based on recombination frequencies. By analyzing how often genes recombine, researchers can create a map that shows the order and distance between genes. This is crucial for predicting inheritance patterns and understanding genetic linkage, which can influence traits in offspring.
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Mapping Overview
Linkage and Gene Order
Linkage refers to the tendency of genes located close to each other on a chromosome to be inherited together. The order of genes can be inferred from recombination frequencies; genes that are further apart are more likely to recombine. Understanding the linkage and order of genes G, T, and R is essential for accurately drawing genetic maps and predicting recombination outcomes.
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