Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
2. Mendel's Laws of Inheritance
Monohybrid Cross
2:02 minutes
Problem 10g
Textbook Question
Textbook QuestionThe dorsal pigment pattern of frogs can be either 'leopard' (white pigment between dark spots) or 'mottled' (pigment between spots appears mottled). The trait is controlled by an autosomal gene. Males and females are selected from pure-breeding populations, and a pair of reciprocal crosses is performed. The cross results are shown below.
Cross 1: P₁: Male leopard x male mottled
F₁: All mottled
F₂: 70 mottled, 22 leopard
Cross 2: P₁: Male mottled x female leopard
F₁: All mottled
F₂: 50 mottled, 18 leopard
Compare and contrast the results of the reciprocal crosses in the context of autosomal gene inheritance.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Autosomal Inheritance
Autosomal inheritance refers to the transmission of genes located on the autosomes, which are the non-sex chromosomes. Traits controlled by autosomal genes can be dominant or recessive. In this case, the dorsal pigment pattern in frogs is influenced by an autosomal gene, where the mottled phenotype appears to be dominant over the leopard phenotype, as indicated by the F₁ generation showing all mottled offspring.
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Reciprocal Crosses
Reciprocal crosses involve mating individuals of different phenotypes in both possible combinations to determine the influence of parental genotypes on offspring traits. In this scenario, both crosses produced F₁ offspring that were all mottled, suggesting that the mottled trait is dominant. The comparison of F₂ offspring ratios from both crosses helps to confirm the inheritance pattern and assess any potential sex-linked effects.
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Phenotypic Ratios
Phenotypic ratios represent the relative frequencies of different phenotypes in the offspring resulting from a genetic cross. In the F₂ generation of the first cross, the ratio of mottled to leopard frogs was approximately 3:1, while in the second cross, it was closer to 3:1 as well. These ratios provide insight into the inheritance patterns and dominance relationships of the traits being studied, reinforcing the conclusion about the dominance of the mottled phenotype.
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