Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
2. Mendel's Laws of Inheritance
Pedigrees
1:36 minutes
Problem 47c
Textbook Question
Textbook QuestionThe accompanying pedigree shows a family in which one child (II-1) has an autosomal recessive condition. On the basis of this fact alone, provide the following information.
What are the probabilities for each of the possible genotypes for II-2, II-3, and II-4?
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Autosomal Recessive Inheritance
Autosomal recessive inheritance occurs when a trait or condition is expressed only when an individual has two copies of the recessive allele, one inherited from each parent. In this case, if a child has an autosomal recessive condition, both parents must be carriers of the recessive allele, even if they do not express the condition themselves.
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Autosomal Pedigrees
Pedigree Analysis
A pedigree is a diagram that depicts the genetic relationships within a family over generations. It helps in tracking the inheritance of traits and can reveal patterns of inheritance, such as whether a condition is autosomal dominant or recessive, by analyzing the affected and unaffected individuals in the family.
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Pedigree Flowchart
Genotype Probabilities
Genotype probabilities refer to the likelihood of an individual inheriting a specific combination of alleles from their parents. In the context of the pedigree, calculating the probabilities for genotypes of II-2, II-3, and II-4 involves using the known genotypes of their parents and applying principles of Mendelian genetics to determine the chances of each possible genotype.
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Probability
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