Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
10. Transcription
Overview of Transcription
2:25 minutes
Problem 4
Textbook Question
Textbook QuestionIdentify similarities and differences between an inducible operon and a repressible operon in terms of
the transcription-regulating DNA sequences.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Operons
Operons are clusters of genes under the control of a single promoter, allowing coordinated regulation of gene expression in prokaryotes. They consist of structural genes, a promoter, and regulatory sequences. Understanding operons is crucial for analyzing how genes are turned on or off in response to environmental changes.
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Inducible Operons
Inducible operons are typically off but can be activated in response to specific signals, such as the presence of a substrate. The classic example is the lac operon, which is activated when lactose is available, allowing the transcription of genes needed for lactose metabolism. This mechanism enables bacteria to adapt to changing nutrient conditions.
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04:29
Induced Mutations
Repressible Operons
Repressible operons are usually active but can be inhibited by specific molecules, often end products of a metabolic pathway. A well-known example is the trp operon, which is repressed when tryptophan levels are high, preventing the synthesis of tryptophan when it is abundant. This feedback mechanism helps maintain homeostasis within the cell.
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