Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
4. Genetic Mapping and Linkage
Chi Square and Linkage
4:09 minutes
Problem 15a
Textbook Question
Textbook QuestionThree dominant traits of corn seedlings, tunicate seed (T-), glossy appearance (G-), and liguled stem (L-), are studied along with their recessive counterparts, nontunicate (tt), nonglossy (gg), and liguleless (ll). A trihybrid plant with the three dominant traits is crossed to a nontunicate, nonglossy, liguleless plant. Kernels on ears of progeny plants are scored for the traits, with the following results: Phenotype Number Tunicate, glossy, liguled 102 Tunicate, glossy, liguleless 106 Tunicate, nonglossy, liguled 18 Tunicate, nonglossy, liguleless 20 Nontunicate, glossy, liguled 22 Nontunicate, glossy, liguleless 23 Nontunicate, nonglossy, liguled 99 Nontunicate, nonglossy, liguleless 110 500 Could all three genes be carried on the same chromosome? Discuss why or why not.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Gene Linkage
Gene linkage refers to the tendency of genes located close to each other on the same chromosome to be inherited together during meiosis. If genes are linked, they do not assort independently, which can affect the expected phenotypic ratios in offspring. In this case, analyzing the ratios of the traits in the progeny can help determine if the genes for tunicate seed, glossy appearance, and liguled stem are linked or assort independently.
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Independent Assortment
Independent assortment is a principle of genetics stating that alleles for different traits segregate independently of one another during gamete formation. This concept is crucial for understanding Mendelian inheritance patterns. If the traits in the corn seedlings exhibit a 9:3:3:1 ratio in the progeny, it suggests that the genes are assorting independently, indicating they are likely on different chromosomes.
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Chi-Square Analysis
Chi-square analysis is a statistical method used to determine if there is a significant difference between observed and expected frequencies in genetic crosses. By applying this test to the phenotypic ratios of the progeny, one can assess whether the observed distribution aligns with the expected ratios for independent assortment or suggests linkage. This analysis is essential for drawing conclusions about the genetic arrangement of the traits in question.
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