Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
15. Genomes and Genomics
Comparative Genomics
1:15 minutes
Problem 24b
Textbook Question
Textbook QuestionDominguez et al. (2004) suggest that by studying genes that determine growth and tissue specification in the eye of Drosophila, much can be learned about human eye development.
What evidence indicates that the eyeless gene is part of a developmental network?
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Key Concepts
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Eyeless Gene
The eyeless gene in Drosophila is a critical gene that regulates eye development. It encodes a transcription factor that initiates the formation of eye tissues. Mutations in this gene can lead to the absence of eyes, demonstrating its essential role in ocular development. Understanding its function provides insights into similar genetic mechanisms in other organisms, including humans.
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Mapping Genes
Developmental Gene Networks
Developmental gene networks are interconnected groups of genes that work together to control the development of specific tissues and organs. These networks involve signaling pathways and regulatory interactions that ensure proper timing and spatial expression of genes during development. The eyeless gene is part of such a network, influencing and being influenced by other genes that contribute to eye formation.
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Segmentation Genes
Conservation of Genetic Pathways
Conservation of genetic pathways refers to the phenomenon where similar genetic mechanisms are preserved across different species through evolution. This concept suggests that studying model organisms like Drosophila can reveal fundamental biological processes applicable to humans. Evidence of the eyeless gene's role in eye development in fruit flies supports the idea that analogous genes may function similarly in human eye development.
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Repair Pathways
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