Experimental evidence demonstrates that the nucleosomes ...

Question

Experimental evidence demonstrates that the nucleosomes present in a cell after the completion of S phase are composed of some 'old' histone dimers and some newly synthesized histone dimers. Describe the general design for an experiment that uses a protein label such as ³⁵S to show that nucleosomes are often a mixture of old and new histone dimers following DNA replication.

Accepted Answer

Hi, everyone. Let's look at our next question. It says which of the following his stones links the nucleosome together. And our answers are A H one BH A CH 2 B DH 3 4 EH 4. Well, let's take a moment to recall from our content video, what the his stones are and their involvement with the nucleosome. And we recall that chromatin is structured in a sort of what's called beads on a string structure. And so we've got these histone cores that have DNA sort of wound around them kind of spiraled around them. Excuse the poor drawing here. I'm drawing sort of a cluster of little circles with in blue, with red lines, sort of spiraling around them like a, like a string and then linking it between them. And this core that they're wrapped around is an aimer of his stone proteins. And then each of these that core with the DNA wrapped around it are the beads in our beads on a string structure here and the string or the linkage there is composed of link or DNA bound to histone protein. And our question of course is asking us which of the his toes links the nucleosome together. So, what we're looking for is the histone protein that is bound to the link or DNA binding together each nucleosome. And that histone protein is choice A H one, all of these other choices, H two, A H, two, B H three and H four are other answer. Choices B through E are the proteins that make up the aimer. So they're the core of the bead of each nucleosome. And our answer for which of the following his stones links the nucleosome together is choice AH 1. See you in the next video.

My Courses

Chemistry

Biology

Math

Physics

Business

Social Sciences

Programming

Product & Marketing