19. Cancer Genetics
Overview of Cancer
1:46 minutes
Problem 3a
Textbook Question
Textbook QuestionFor the retinal cancer retinoblastoma, the inheritance of one mutated copy of RB1 from one of the parents is often referred to as a mutation that produces a 'dominant predisposition to cancer.' This means that the first mutation does not produce cancer but makes it very likely that cancer will develop. Define the 'two-hit hypothesis' for retinoblastoma.
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