Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
6. Chromosomal Variation
Chromosomal Rearrangements: Translocations
1:54 minutes
Problem 13c
Textbook Question
Textbook QuestionAn animal heterozygous for a reciprocal balanced translocation has the following chromosomes:
MN • OPQRST
MN • OPQRjkl
cdef • ghijkl
cdef • ghiST
Identify the gametes produced by adjacent-1 segregation. Which if any of these gametes are viable?
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Reciprocal Balanced Translocation
A reciprocal balanced translocation occurs when two chromosomes exchange segments without any loss of genetic material. This results in a rearrangement of genes but maintains the overall genetic balance. In organisms with such translocations, the chromosomes can pair during meiosis, leading to unique segregation patterns that can affect gamete viability.
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Reciprocal Translocation
Adjacent-1 Segregation
Adjacent-1 segregation is a specific way chromosomes can segregate during meiosis in individuals with reciprocal translocations. In this process, one chromosome from each pair of homologous chromosomes is selected, leading to gametes that contain both segments from the translocated chromosomes. This type of segregation often results in gametes that are unbalanced, which can affect their viability.
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Reciprocal Translocation
Gamete Viability
Gamete viability refers to the ability of gametes to develop into a viable organism after fertilization. In the context of adjacent-1 segregation, the resulting gametes may have an unbalanced genetic composition, which can lead to non-viable embryos or developmental issues. Understanding which gametes are viable is crucial for predicting the outcomes of genetic crosses involving translocations.
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