Tay–Sachs disease is an autosomal recessive neurological disorder...

Question

Tay–Sachs disease is an autosomal recessive neurological disorder that is fatal in infancy. Despite its invariably lethal effect, Tay–Sachs disease occurs at very high frequency in some Central and Eastern European (Ashkenazi) Jewish populations. In certain Ashkenazi populations, 1 in 750 infants has Tay–Sachs disease. Population biologists believe the high frequency is a consequence of genetic bottlenecks caused by pogroms (genocide) that have reduced the population multiple times in the past several hundred years.

What is a genetic bottleneck?

Accepted Answer

Hello everyone and welcome to today's video. So which of the following altars the frequencies in our population that survives a catastrophic event. As the answer choice. A we have mutation d genetic bottleneck C founder effect the ingredient. So let's go over each of these. So we may solve the problem beginning by a mutation. So a mutation involves a change in the genes of a certain organism. This is usually going to be used to, for example, introduce new all into a population. So it's going to increase genetic diversity. However, this really doesn't involve a catastrophic event for imitation to happen. So we're going to cancel this power. Then we have a founder effect. Founder effect involves a very small part of a larger population breaking off and founding a new population apart from them. This is usually going to decrease genetic diversity. However, this does not involve a catastrophic event. So we're going to cancel it up. Then we have inbreeding. Inbreeding involves meeting with individuals that are related to you. This really does not involve a catastrophic event either for this to happen. So we're going to cancel this out and then we have the genetic bottleneck. So and doing a genetic bottleneck, we have a population with many different all or genes. So this population is going to undergo a catastrophic event which is going to lead to the reduction of genetic diversity. So this is what their problem is. Meaning when they states that it alters the all of frequencies, it alters the genetic diversity of a certain population after a catastrophic event such as a tsunami or a flood happens. And many of the individuals are killed off. The fourth answer choice. B genetic bottleneck is going to be the correct answer for this question. I really hope it's helped and I hope to see you on the next video.

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