Go to the OMIM website (http://www.ncbi.nlm.nih.gov/omim...

Question

Go to the OMIM website (http://www.ncbi.nlm.nih.gov/omim) and locate the Search button at the top of the page. Use the Search function to look up, one by one, the following three human hereditary diseases that are relatively common in certain populations: 'Tay–Sachs disease' (select OMIM number 272800 from the search results list); 'cystic fibrosis' (select OMIM number 602421 from the search results list); and 'sickle cell anemia' (select OMIM 603903 from the search results list). For each of these diseases, look through the information and provide the following details:

On which chromosome is the gene for the disease located?

Accepted Answer

Hey, everyone. Let's take a look at this question together, which of the falling inherited disorders is caused by the absence or malfunction of an enzyme called hex. So, Samina Days A located on chromosome 15. So let's recall what we know about the enzyme H E X A that is located on chromosome 15 to figure out what inherited disorder is caused by the absence or malfunction of that enzyme. So we know that H E X A or heck. So Samina Days A is responsible or breaking down a fatty substance that is called GM two Ganglia side. And we note that GM two Ganglia side accumulates in the brain and other organs leading two progressive physical and mental deterioration. And so the production of this H E X A enzyme is actually directed by the H E X A gene which codes for the production of that enzyme. And so an absence or malfunction in H E X A gene which leads to an absence or malfunction of that enzyme H E X A causes the disorder sex disease or answer choice C, The correct answer because Tay Sachs disease, which is a rare inherited disorder is caused by the absence or malfunction of an enzyme called Hex. So Samina days a which is located on chromosome 15. So answer choice C is the correct answer. I hope you found this video to be helpful. Thank you and goodbye.

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