Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
13. Gene Regulation in Eukaryotes
Overview of Eukaryotic Gene Regulation
2:03 minutes
Problem 14
Textbook Question
Textbook QuestionWhat is one proposed role for lncRNAs?
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Long Non-Coding RNAs (lncRNAs)
Long non-coding RNAs (lncRNAs) are a class of RNA molecules that are longer than 200 nucleotides and do not encode proteins. They play crucial roles in regulating gene expression at various levels, including chromatin remodeling, transcription, and post-transcriptional processing. Their diverse functions make them important players in cellular processes and potential targets for therapeutic interventions.
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Gene Regulation
Gene regulation refers to the mechanisms that control the expression of genes, determining when and how much of a gene product is made. This process is essential for maintaining cellular function and responding to environmental changes. lncRNAs can influence gene regulation by interacting with DNA, RNA, or proteins, thereby modulating the activity of specific genes.
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Review of Regulation
Epigenetics
Epigenetics involves changes in gene expression that do not alter the underlying DNA sequence but are heritable and can be influenced by environmental factors. lncRNAs are known to play a role in epigenetic regulation by recruiting chromatin-modifying complexes to specific genomic regions, thereby affecting the accessibility of DNA for transcription and influencing cellular identity and function.
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Chromatin
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