Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
7. DNA and Chromosome Structure
DNA as the Genetic Material
4:40 minutes
Problem 4a
Textbook Question
Textbook QuestionExplain how the Hershey and Chase experiment identified DNA as the hereditary molecule.
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Key Concepts
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Hershey and Chase Experiment
The Hershey and Chase experiment, conducted in 1952, utilized bacteriophages (viruses that infect bacteria) to determine whether DNA or protein was the genetic material. They labeled the DNA with radioactive phosphorus and the protein with radioactive sulfur, then tracked which component entered the bacterial cells. The results showed that only the DNA entered the cells, indicating that DNA is the hereditary molecule.
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Bacteriophages
Bacteriophages, or phages, are viruses that specifically infect bacteria. They consist of a protein coat and genetic material, which can be either DNA or RNA. In the Hershey and Chase experiment, phages were used as a model to study the transfer of genetic information, providing a clear system to distinguish between DNA and protein as the hereditary substance.
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Radioactive Labeling
Radioactive labeling is a technique used to trace the movement of molecules in biological experiments. In the Hershey and Chase experiment, the researchers used radioactive isotopes to label DNA and protein separately. This allowed them to track which component was responsible for carrying genetic information into the bacterial cells, ultimately demonstrating that DNA, not protein, was the hereditary material.
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