Table of contents

1. Introduction to Genetics51m
2. Mendel's Laws of Inheritance3h 37m
3. Extensions to Mendelian Inheritance2h 41m
4. Genetic Mapping and Linkage2h 28m
5. Genetics of Bacteria and Viruses1h 21m
6. Chromosomal Variation1h 48m
7. DNA and Chromosome Structure56m
8. DNA Replication1h 10m
9. Mitosis and Meiosis1h 34m
10. Transcription1h 0m
11. Translation58m
12. Gene Regulation in Prokaryotes1h 19m
13. Gene Regulation in Eukaryotes44m
14. Genetic Control of Development44m
15. Genomes and Genomics1h 50m
16. Transposable Elements47m
17. Mutation, Repair, and Recombination1h 6m
18. Molecular Genetic Tools19m
- Genetic Cloning
  9m
- Methods for Analyzing DNA
  9m
19. Cancer Genetics29m
- Overview of Cancer
  21m
- Cancer Mutations
  7m
20. Quantitative Genetics1h 26m
21. Population Genetics50m
- Hardy Weinberg
  19m
- Allelic Frequency Changes
  31m
22. Evolutionary Genetics29m

5. Genetics of Bacteria and Viruses

Bacteriophage Genetics

Genetics

5. Genetics of Bacteria and Viruses

Bacteriophage Genetics

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2:05 minutes

Problem 22

Textbook Question

In studies of recombination between mutants 1 and 2 from Problem 21, the results shown in the following table were obtained.Strain Dilution Plaques PhenotypesE. coli B 10⁻⁷ 4 rE. coli K12 10⁻² 8 +Calculate the recombination frequency.

Verified step by step guidance

Identify the relevant data from the problem: the number of plaques for each strain and dilution factor.

Understand that recombination frequency is calculated as the number of recombinant plaques divided by the total number of plaques, then multiplied by 100 to get a percentage.

Calculate the number of recombinant plaques by considering the plaques that show a different phenotype from the parent strains.

Determine the total number of plaques by considering the dilution factor and the number of plaques observed.

Use the formula for recombination frequency: (Number of recombinant plaques / Total number of plaques) * 100.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Recombination Frequency

Recombination frequency is a measure of the likelihood that two genes will be separated during meiosis due to crossing over. It is calculated by dividing the number of recombinant offspring by the total number of offspring, often expressed as a percentage. This frequency provides insights into the genetic linkage between genes, with lower frequencies indicating closer linkage.

Genetic Linkage

Genetic linkage refers to the tendency of genes located close to each other on a chromosome to be inherited together during meiosis. Linked genes do not assort independently, which can affect the ratios of phenotypes observed in offspring. Understanding linkage is crucial for interpreting recombination frequencies and mapping genes on chromosomes.

Phenotype and Genotype

Phenotype refers to the observable characteristics or traits of an organism, which result from the interaction of its genotype (the genetic makeup) with the environment. In genetic studies, distinguishing between different phenotypes, such as mutants and wild types, is essential for analyzing inheritance patterns and calculating recombination frequencies.

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Textbook Question

An attribute of growth behavior of eight bacteriophage mutants (1 to 8) is investigated in experiments that establish coinfection by pairs of mutants. The experiments determine whether the mutants complement one another (+) or fail to complement (-). These eight mutants are known to result from point mutation. The results of the complementation tests are shown below.

Identify the mutants of each gene.

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