18. Molecular Genetic Tools
Genetic Cloning
4:59 minutes
Problem 11a
Textbook Question
Textbook QuestionInjection of double-stranded RNA can lead to gene silencing by degradation of RNA molecules complementary to either strand of the dsRNA. Could RNAi (see Sections 13.3 and 14.3) be used in gene therapy for a defect caused by a recessive allele? A dominant allele? If so, what might be the major obstacle to using RNAi as a therapeutic agent?
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