Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
7. DNA and Chromosome Structure
DNA Structure
3:18 minutes
Problem 17d
Textbook Question
Textbook QuestionWhich of the following equalities is not true for double-stranded DNA? (G + A) = (C + T)
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Base Pairing Rules
In double-stranded DNA, the base pairing rules dictate that adenine (A) pairs with thymine (T) and guanine (G) pairs with cytosine (C). This complementary pairing is crucial for the stability of the DNA structure and ensures accurate replication and transcription processes.
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Base Distortions
Chargaff's Rules
Chargaff's rules state that in any double-stranded DNA molecule, the amount of adenine is equal to thymine (A=T) and the amount of guanine is equal to cytosine (G=C). This leads to the conclusion that the total number of purines (A + G) equals the total number of pyrimidines (C + T), which is essential for understanding DNA composition.
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DNA Structure
Double-stranded DNA has a helical structure composed of two strands running in opposite directions, held together by hydrogen bonds between complementary bases. This structure is fundamental to its function in genetic information storage and transmission, and any deviation from the expected base pairing can indicate mutations or errors.
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