Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
20. Quantitative Genetics
Heritability
1:58 minutes
Problem 27a
Textbook Question
Textbook QuestionAnswer the following in regard to multifactorial traits in human twins. If the trait is substantially influenced by genes, would you expect the concordance rate to be higher in MZ twins or higher in DZ twins? Explain your reasoning.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Concordance Rate
Concordance rate refers to the likelihood that both twins in a pair exhibit the same trait or condition. In genetic studies, this measure helps determine the influence of genetics versus environment on traits. A higher concordance rate in monozygotic (MZ) twins compared to dizygotic (DZ) twins suggests a stronger genetic component, as MZ twins share 100% of their genes, while DZ twins share about 50%.
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Monozygotic (MZ) vs. Dizygotic (DZ) Twins
Monozygotic twins, or identical twins, originate from a single fertilized egg that splits into two embryos, resulting in genetically identical individuals. In contrast, dizygotic twins, or fraternal twins, develop from two separate eggs fertilized by two different sperm cells, sharing approximately 50% of their genetic material. This distinction is crucial for understanding the genetic basis of traits, as MZ twins provide insights into the heritability of traits.
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Twin Studies
Multifactorial Traits
Multifactorial traits are characteristics influenced by multiple genes and environmental factors, making their inheritance complex. Examples include height, intelligence, and susceptibility to diseases. In the context of twins, examining concordance rates for multifactorial traits helps researchers understand the relative contributions of genetic predisposition and environmental influences, providing insights into how these traits are expressed in individuals.
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