Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
4. Genetic Mapping and Linkage
Crossing Over and Recombinants
1:53 minutes
Problem 19
Textbook Question
Textbook QuestionIf the cross described in Problem 18 were made, and if Sb and cu are 8.2 map units apart on chromosome III, and if 1000 offspring were recovered, what would be the outcome of the cross, assuming that equal numbers of males and females were observed?
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Genetic Mapping
Genetic mapping is a method used to determine the location of genes on a chromosome and the distance between them. The distance is often measured in map units, where 1 map unit corresponds to a 1% chance of recombination occurring between two genes during meiosis. In this case, the distance of 8.2 map units between the Sb and cu genes indicates a relatively low frequency of recombination, which affects the expected offspring ratios.
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Mapping Overview
Recombination Frequency
Recombination frequency refers to the likelihood that two genes will be separated during meiosis due to crossing over. It is calculated as the number of recombinant offspring divided by the total number of offspring. In the context of the question, a recombination frequency of 8.2% suggests that 8.2% of the offspring will exhibit recombinant phenotypes, while the remaining 91.8% will show parental phenotypes.
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Recombination after Single Strand Breaks
Offspring Ratios in Genetic Crosses
In genetic crosses, the expected ratios of offspring phenotypes can be predicted based on the principles of inheritance and recombination. For a cross involving linked genes, the expected outcome can be calculated by considering both parental and recombinant types. Given the recombination frequency and the total number of offspring (1000), one can determine the expected number of each phenotype, which helps in analyzing the results of the cross.
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