Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
11. Translation
Transfer RNA
2:34 minutes
Problem 8b
Textbook Question
Textbook QuestionFor each of the anticodon sequences given in the previous problem, identify the other codon sequence to which it could potentially pair using third base wobble.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Anticodon and Codon Pairing
Anticodons are sequences of three nucleotides in tRNA that pair with complementary codons in mRNA during translation. Each codon in mRNA corresponds to a specific amino acid, and the pairing is crucial for accurate protein synthesis. Understanding how anticodons match with codons is essential for interpreting genetic information.
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Translation:Wobble Hypothesis
Wobble Hypothesis
The wobble hypothesis explains how the third base of a codon can be less specific in pairing with the corresponding anticodon. This flexibility allows a single tRNA to recognize multiple codons that code for the same amino acid, enhancing the efficiency of protein synthesis. This concept is vital for understanding the redundancy in the genetic code.
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Translation:Wobble Hypothesis
Genetic Code Redundancy
The genetic code is described as redundant because multiple codons can encode the same amino acid. This redundancy is a result of the 64 possible codons (combinations of three nucleotides) coding for only 20 amino acids. Recognizing this redundancy is important for predicting how different codons can pair with anticodons, especially when considering wobble pairing.
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The Genetic Code
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