Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
18. Molecular Genetic Tools
Methods for Analyzing DNA
2:05 minutes
Problem 29a
Textbook Question
Textbook QuestionA three-gene system of additive genes (A, B, and C) controls plant height. Each gene has two alleles (A and a, B and b, and C and c). There is dominance among the alleles of each gene, with alleles A, B, and C dominant over a, b, and c. Under this scheme, the dominant genotype for a gene contributes 10 cm to height potential, and the recessive genotype contributes 4 cm. What are the phenotypes and proportions of each phenotype among the F₂?
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Additive Gene Action
Additive gene action refers to the cumulative effect of multiple genes on a single trait, where each dominant allele contributes a specific amount to the phenotype. In this case, the three genes (A, B, and C) each add to the plant height, with dominant alleles contributing more than recessive ones. Understanding this concept is crucial for predicting the overall phenotype based on the combination of alleles present.
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Mapping Genes
Genotype and Phenotype
The genotype is the genetic makeup of an organism, while the phenotype is the observable expression of that genotype. In this scenario, the different combinations of alleles (AA, Aa, aa, etc.) will determine the plant's height, which is the phenotype. Recognizing how genotypes translate into phenotypes is essential for determining the proportions of each phenotype in the offspring.
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Punnett Square and F₂ Generation
A Punnett square is a tool used to predict the genetic outcomes of a cross between two organisms. In the F₂ generation, the offspring are produced from the self-fertilization of F₁ hybrids, allowing for a variety of genotype combinations. Analyzing the Punnett square for the three-gene system will help determine the expected phenotypic ratios among the F₂ plants based on the additive effects of the alleles.
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