In the globin gene family shown in Figure 16.16, which p...

Question

In the globin gene family shown in Figure 16.16, which pair of genes would exhibit a higher level of sequence similarity, the human δ-globin and human β-globin genes or the human β-globin and chimpanzee β-globin genes? Can you explain your answer in terms of timing of gene duplications?

Accepted Answer

Hello, everyone and welcome to today's video. So in the annex gene family found in humans, mice and chickens, namely a one, a two, a three and a four, the protein sequence identities between the human and mouse genes are a 1 89%. A 2 95% a 3 85% and a four 88%. The protein sequence identities between the humans and chicken genes or a 1 64%. A 2 70% a 3 65% and a 4 67%. Now, which two genes exhibit a higher level of sequence similarity. Now, as answer choice A, we have the A one genes in humans and mice as answer choice B, we have the A three genes in humans and chickens as answer choice C, we have the A two genes in humans and mice and as answer choice D, we have the A four genes in humans and chickens. So although this question is very long, it can be solved very simply because we just have to look at these percentage similarities between the genes that we are given. So let's go over each of our answer choices. And just write down next to them the percentage similarity given in the problem beginning by answer choice. A we have the A one genes in humans and mice, which is going to be underlying here. It is stated to have an 89% sequence similarity. So let's write that down there. Moving on, we have B which is the A three genes in humans and chickens. So in humans and chickens, the A three gene has a percent similarity of 65% as under liner. Now we're going to write that down next to the answer choice. Moving on, we have C the A two genes in humans and mice. So again, the A two genes in humans and mice is going to have a percentage similarity as given here of 95%. So let's write that down moving on. And finally, we have the, the A four genes in humans and chickens. And if we look at the problem, we're given that the A four gene has a percentage similarity of 67%. So we can write that down. So all we have to look at here is the highest number which is going to be this 95%. So the percentage similarity of the A two genes in humans and mice is the highest one. So we're going to highlight answer to C A two genes in humans and mice as a final answer to our question, I really hope this helped you and I hope to see you on the next video.

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In the globin gene family shown in Figure 16.16, which pair of genes would exhibit a higher level of sequence similarity, the human δ-globin and human β-globin genes or the human β-globin and chimpanzee β-globin genes? Can you explain your answer in terms of timing of gene duplications?