Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
7. DNA and Chromosome Structure
DNA Structure
2:44 minutes
Problem 1b
Textbook Question
Textbook QuestionHow do we know that G pairs with C and that A pairs with T as complementary base pairs are formed?
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Complementary Base Pairing
Complementary base pairing refers to the specific pairing of nitrogenous bases in DNA and RNA. In DNA, adenine (A) pairs with thymine (T), and cytosine (C) pairs with guanine (G). This pairing is due to hydrogen bonding, where A forms two hydrogen bonds with T, and C forms three hydrogen bonds with G, ensuring the stability and integrity of the DNA double helix.
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Chargaff's Rules
Chargaff's rules state that in a given DNA molecule, the amount of adenine equals the amount of thymine, and the amount of cytosine equals the amount of guanine. This observation was crucial in understanding the structure of DNA, as it provided evidence for the complementary nature of base pairing, which is fundamental to DNA replication and transcription.
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DNA Structure
The structure of DNA is a double helix formed by two strands of nucleotides running in opposite directions. Each nucleotide consists of a sugar, a phosphate group, and a nitrogenous base. The specific arrangement of these bases along the strands, with A pairing with T and C pairing with G, allows for the encoding of genetic information and the faithful transmission of this information during cell division.
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