Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
6. Chromosomal Variation
Chromosomal Rearrangements: Translocations
1:28 minutes
Problem 13e
Textbook Question
Textbook QuestionAn animal heterozygous for a reciprocal balanced translocation has the following chromosomes:
MN • OPQRST
MN • OPQRjkl
cdef • ghijkl
cdef • ghiST
Diagram the pairing of these chromosomes in prophase I.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Heterozygous Reciprocal Balanced Translocation
A heterozygous reciprocal balanced translocation occurs when two non-homologous chromosomes exchange segments, resulting in a rearrangement of genetic material. In this case, one chromosome carries one arrangement of genes, while its homologous partner carries a different arrangement. This can affect gene expression and segregation during meiosis, but if balanced, it typically does not lead to a loss of genetic material.
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Reciprocal Translocation
Prophase I of Meiosis
Prophase I is the first stage of meiosis, where homologous chromosomes pair up and exchange genetic material through a process called crossing over. This stage is crucial for genetic diversity, as it allows for the recombination of alleles. The pairing of chromosomes, known as synapsis, forms structures called tetrads, which consist of four chromatids, facilitating the exchange of segments between homologous chromosomes.
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Meiosis Steps
Chromosome Pairing and Diagramming
Diagramming chromosome pairing involves visually representing how chromosomes align during prophase I. In the case of a heterozygous reciprocal balanced translocation, the diagram must show the unique arrangements of the involved chromosomes, indicating how they pair and where crossing over may occur. This visual representation helps in understanding the genetic implications of the translocation and the potential outcomes for gametes.
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Branch Diagram
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