Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
6. Chromosomal Variation
Chromosomal Mutations: Aneuploidy
2: minutes
Problem 17a
Textbook Question
Textbook QuestionDrosophila may be monosomic for chromosome 4, yet remain fertile. Contrast the F₁ and F₂ results of the following crosses involving the recessive chromosome 4 trait, bent bristles: monosomic IV, normal bristles x diploid, bent bristles.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Monosomy
Monosomy refers to the condition where an organism has only one copy of a particular chromosome instead of the usual two. In Drosophila, being monosomic for chromosome 4 means that there is only one copy of this chromosome present. This can lead to specific phenotypic expressions, such as the potential for fertility despite the loss of genetic material, which is crucial for understanding the genetic outcomes in the given crosses.
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Aneuploidy
Recessive Traits
Recessive traits are characteristics that are expressed only when an individual has two copies of the recessive allele. In the context of the bent bristles trait in Drosophila, this means that a fly must inherit the bent bristles allele from both parents to exhibit the phenotype. Understanding how these traits segregate during crosses is essential for predicting the phenotypic ratios in the F₁ and F₂ generations.
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Traits and Variance
Genetic Crosses and Segregation
Genetic crosses involve mating individuals to observe the inheritance patterns of specific traits. The F₁ generation results from the initial cross, while the F₂ generation arises from self-fertilization or intercrossing of F₁ individuals. The principles of segregation, as described by Mendel, dictate how alleles are distributed to offspring, which is vital for analyzing the outcomes of the crosses involving monosomic and diploid individuals in the question.
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Trihybrid Cross
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