Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
11. Translation
The Genetic Code
2:49 minutes
Problem 21e
Textbook Question
Textbook QuestionIn an experiment to decipher the genetic code, a poly-AC mRNA (ACACACAC...) is synthesized. What pattern of amino acids would appear if this sequence were to be translated by a mechanism that reads the genetic code as
a doublet with overlaps?
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Genetic Code
The genetic code is a set of rules that defines how the sequence of nucleotides in mRNA is translated into amino acids. It consists of codons, which are triplets of nucleotides, each corresponding to a specific amino acid or a stop signal during protein synthesis. Understanding the genetic code is essential for predicting the amino acid sequence from an mRNA strand.
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Doublet Codons
Doublet codons refer to a hypothetical reading frame where the genetic code is interpreted in pairs of nucleotides instead of the standard triplet codons. This means that each amino acid would be determined by two adjacent nucleotides, leading to a different pattern of amino acid sequences than what is typically expected from standard translation.
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Overlapping Reading Frames
Overlapping reading frames occur when the same nucleotide sequence can be read in multiple ways, allowing for different sets of codons to be formed from the same sequence. This can lead to the production of different proteins from a single mRNA strand, depending on how the reading frame is shifted or interpreted, which is crucial for understanding the potential outcomes of translating the poly-AC mRNA.
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