8. DNA Replication
Overview of DNA Replication
1:39 minutes
Problem 20f
Textbook Question
Textbook QuestionDNA supercoiling, which occurs when coiling tension is generated ahead of the replication fork, is relieved by DNA gyrase. Supercoiling may also be involved in transcription regulation. Researchers discovered that enhancers operating over a long distance (2500 bp) are dependent on DNA supercoiling, while enhancers operating over shorter distances (110 bp) are not so dependent [Liu et al. (2001). Proc. Natl. Acad. Sci. USA 98:14,883–14,888]. Using a diagram, suggest a way in which supercoiling may positively influence enhancer activity over long distances.
Verified Solution
This video solution was recommended by our tutors as helpful for the problem above
Video duration:
1mPlay a video:
390
views
Was this helpful?
Related Videos
Related Practice